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NETS - Phase I Clinical Trials (PK, Safety, Dose)

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What are Phase I clinical trials and why are they important in drug development?

In Phase I clinical trials researchers test a new drug or treatment on a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects: in other words, they study its safety and dose. The pharmacokinetics (PK) of the drug or therapy - are examined as well. The participants in Phase I trials are healthy or unaffected volunteers.

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