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NETS - Acute Toxicology

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What is acute toxicology and why is it important in drug development?

Acute toxicology describes the adverse effects of a substance that result from a single dose or multiple doses administered in close succession. The adverse events occur a short time after the substance is administered. Acute toxicology is used to determine the pharmacological effects of different doses, including the lethal dose, and produce a description of the effects resulting from a single or repeated exposure. This data helps predict the safety of a compound in humans, and helps guide the dosing in clinical studies.

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