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What is disease pathophysiology and why is it important in drug development?

Disease Pathophysiology is the study of how disease alters the functions of cells, organs, organ systems, and how these changes in turn affect the entire body. To learn more about disease pathophysiology and why characterizing it is important for drug development, click on the links below.

• Sage Bionetworks: Case Studies

Testimonials: How we did it

Relevant publications

• Sage Bionetworks: Network Biology Resources
• Sage Bionetworks: The Need for Precompetitive Integrative Bionetwork Disease Model Building
• Sage Bionetworks: Developing Predictive Molecular Maps of Human Disease through Community-Based Modeling
• Sage Bionetworks: Genetics of Gene Expression and Its Effects on Disease
• Sage Bionetworks: An Integrative Genomics Approach to Infer Casual Associations between Gene Expression and Disease
• Sage Bionetworks: Molecular Networks as Sensors and Drivers of Common Human Diseases

Related Tools

• Genetic Alliance: Disease InfoSearch
• NCBI: PubMed
• NCBI: dbGaP
• NIDDK: Data, Biosample, and Genetics Repository
• NIA and the Coriell Institute: Aging Cell Repository
• NIH, NHGRI: The Cancer Genome Atlas Data PortalP
• Sage Bionetworks: Repository