The Genetic Information Nondiscrimination Act (GINA) provides a baseline for protection against genetic discrimination for all Americans. However, GINA does not preempt state anti-discrimination law that provides more extensive protections than GINA, either in health insurance or employment. To determine compliance with both state and federal law, states will need to compare GINA to the current state laws in place and be sure to comply with the highest level of protection provided by the legislation.