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What are molecular pathways and why are they important in drug development?

Molecular pathways are a series of interactions that occur between molecules within a cell and between cells. Understanding the molecular pathways that drive or are affected by disease has a critical role in helping scientists select the best therapeutic targets. To learn more about molecular pathways and why they are important for drug development, click on the links below.

• NIGMS: “No Lab, No Problem!” from The New Genetics
• Sage Bionetworks: Case Studies

Testimonials: How we did it

Relevant publications

Understanding the Role of Molecular Pathways in Disease

• Sage Bionetworks: Network Biology Resources
• Sage Bionetworks: A Network View of Disease and Compound Screening
• Sage Bionetworks: Molecular Networks as Sensors and Drivers of Common Human Diseases
• Sage Bionetworks: The Need for Precompetitive Integrative Bionetwork Disease Model Building
• Sage Bionetworks: Developing Predictive Molecular Maps of Human Disease through Community-Based Modeling

Related Tools

• NCBI: PubMed
• WikiPathways
• Sage Bionetworks: Repository
• Sage Bionetworks: Key Driver Analysis Tool
• The Jackson Laboratory: Mouse Genome Informatics